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13 pages, 1100 KiB  
Article
Phenolic Compounds, Fatty Acid Composition, and Antioxidant Activities of Some Flaxseed (Linum usitatissimum L.) Varieties: A Comprehensive Analysis
by Mehmet Zeki Ko?ak
Processes 2024, 12(4), 689; https://doi.org/10.3390/pr12040689 (registering DOI) - 29 Mar 2024
Abstract
Flaxseed, also known as flax or linseed (Linum usitatissimum L.), is one of the oldest crops. It is used for oil and fiber production. The species displays a broad range of biological activities due to its chemical compounds. It has a widespread [...] Read more.
Flaxseed, also known as flax or linseed (Linum usitatissimum L.), is one of the oldest crops. It is used for oil and fiber production. The species displays a broad range of biological activities due to its chemical compounds. It has a widespread geographical distribution, and a large number of its varieties have been evaluated for their biological efficacy and nutritional value. This study investigates fifteen varieties of the species, some of which are examined for the first time. In this regard, a series of chemical composition analyses and antioxidant assays were carried out. Accordingly, total phenolic content ranged between 613.6 (Michael) and 3164.6 (Atalanta) mg GAE/g, whilst total flavonoid content varied from 176.25 (BonnyDoon) to 689.20 (Mcduff) mg QE/g. Regarding the radical scavenging assays, the values obtained were significantly higher than those of the standard antioxidant (ascorbic acid). Furthermore, the extracts exhibited chelating activity for ferrous ions and a cupric reducing capacity that was comparable to that of the standard. The oil content values of the varieties ranged from 0.82 g/100 g (Michael) to 2.14 g/100 g (McGregor). The percentage of α-linolenic acid varied between 39.21% (McGregor) and 54.13% (Nareum). Full article
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16 pages, 7819 KiB  
Article
Thermo-Mechanical Coupling Analysis of the Sealing Structure Stress of LNG Cryogenic Hose Fittings
by Liang Yang, Miaoer Liu, Yun Liu, Tao Zhang, Hailong Lu, Qingzhen Lu and Jun Yan
J. Mar. Sci. Eng. 2024, 12(4), 581; https://doi.org/10.3390/jmse12040581 (registering DOI) - 29 Mar 2024
Abstract
A cryogenic hose is used to transport liquefied natural gas at sea, where flexible fittings are sealed by corrugated lining and end flange welding. However, the extreme cryogenic temperatures of the conveyed fluid introduce substantial challenges to the integrity of the fitting seals’ [...] Read more.
A cryogenic hose is used to transport liquefied natural gas at sea, where flexible fittings are sealed by corrugated lining and end flange welding. However, the extreme cryogenic temperatures of the conveyed fluid introduce substantial challenges to the integrity of the fitting seals’ structure during the LNG transfer process. In order to study the sealing performance of the fitting under LNG conveying conditions, this paper was based on the general finite element software ABAQUS 6.11 to carry out a thermo-mechanical coupling analysis of the end sealing stress. This paper also established a sealing performance analysis model of the corrugated fitting welding area under the fitting action of LNG load and internal pressure load. A sensitivity analysis was conducted on the influence of weld clearance, blunt edge size, and weld residual height on the weld stress of a fitting ring. The results show that, under the combined action of the medium internal pressure and cryogenic load, the size design of the weld area significantly affects the sealing performance of the fitting, among which the equivalent force of the weld clearance butt sealing area has the greatest impact. Moreover, it was found that a pressure of 5 MPa was 2 mm when the weld clearance was 2 mm, and the average stress at the weld was 53.68 MPa. Further, considering the synergistic influence of the blunt edge size, the weld clearance was 3 mm, the stress was minimal when the blunt side size was 4 mm, and the average stress was 17.42 MPa. These research results can serve as a reference for the design and analysis of the sealing structure of non-adhesive inner corrugated cryogenic hose fittings. Full article
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11 pages, 276 KiB  
Article
Factors That Most Influence the Choice for Fast Food in a Sample of Higher Education Students in Portugal
by Leandro Oliveira and António Raposo
Nutrients 2024, 16(7), 1007; https://doi.org/10.3390/nu16071007 (registering DOI) - 29 Mar 2024
Abstract
The frequency of fast food consumption among higher education students is high, causing worrying implications for public health. This study aims to relate the factors that influence the choice for fast food with social factors, nutritional status, and fast food consumption in a [...] Read more.
The frequency of fast food consumption among higher education students is high, causing worrying implications for public health. This study aims to relate the factors that influence the choice for fast food with social factors, nutritional status, and fast food consumption in a sample of higher education students in Portugal. An online questionnaire was developed and disseminated by social networks among students during the first half of 2023. Two hundred and thirty-seven students participated, mainly female (65.4%), who were attending public higher education institutions (59.1%), with a median of age of 20.0 (19.0; 22.0) years, and about 20% of the sample had overweight. Approximately 80% consumed fast food, and almost 40% consumed it more than once or twice a week. Predominantly (78.0%), they chose hamburger meals, spending EUR 8.0 per meal. The factors that most influenced the choice of fast food were ease or convenience of preparation (59.9%), price (48.5%), and flavor (28.3%). There were also differences between sexes and between those attending public and private higher education institutions regarding whether they usually consume fast food or not. The body mass index was positively associated with age (r: 0.142; p = 0.029) and with fast food spending (r: 0.146; p = 0.024). The results have implications for public health and clinical nutrition, and can support more effective strategies to improve food choices in higher education students. Full article
(This article belongs to the Special Issue Healthy Eating and Determinants of Food Choice)
14 pages, 4211 KiB  
Article
Transcriptomic Changes in Cisplatin-Resistant MCF-7 Cells
by Araceli Ruiz-Silvestre, Alfredo Garcia-Venzor, Gisela Ceballos-Cancino, José M. Sánchez-López, Karla Vazquez-Santillan, Gretel Mendoza-Almanza, Floria Lizarraga, Jorge Melendez-Zajgla and Vilma Maldonado
Int. J. Mol. Sci. 2024, 25(7), 3820; https://doi.org/10.3390/ijms25073820 (registering DOI) - 29 Mar 2024
Abstract
Breast cancer is a leading cause of cancer-related deaths among women. Cisplatin is used for treatment, but the development of resistance in cancer cells is a significant concern. This study aimed to investigate changes in the transcriptomes of cisplatin-resistant MCF7 cells. We conducted [...] Read more.
Breast cancer is a leading cause of cancer-related deaths among women. Cisplatin is used for treatment, but the development of resistance in cancer cells is a significant concern. This study aimed to investigate changes in the transcriptomes of cisplatin-resistant MCF7 cells. We conducted RNA sequencing of cisplatin-resistant MCF7 cells, followed by differential expression analysis and bioinformatic investigations to identify changes in gene expression and modified signal transduction pathways. We examined the size and quantity of extracellular vesicles. A total of 724 genes exhibited differential expression, predominantly consisting of protein-coding RNAs. Notably, two long non-coding RNAs (lncRNAs), NEAT1 and MALAT, were found to be dysregulated. Bioinformatic analysis unveiled dysregulation in processes related to DNA synthesis and repair, cell cycle regulation, immune response, and cellular communication. Additionally, modifications were observed in events associated with extracellular vesicles. Conditioned media from resistant cells conferred resistance to wild-type cells in vitro. Furthermore, there was an increase in the number of vesicles in cisplatin-resistant cells. Cisplatin-resistant MCF7 cells displayed differential RNA expression, including the dysregulation of NEAT1 and MALAT long non-coding RNAs. Key processes related to DNA and extracellular vesicles were found to be altered. The increased number of extracellular vesicles in resistant cells may contribute to acquired resistance in wild-type cells. Full article
(This article belongs to the Section Molecular Biology)
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24 pages, 3618 KiB  
Article
Acridine–Isoxazole and Acridine–Azirine Hybrids: Synthesis, Photochemical Transformations in the UV/Visible Radiation Boundary Region, and Anticancer Activity
by Ekaterina E. Galenko, Mikhail S. Novikov, Alexander S. Bunev and Alexander F. Khlebnikov
Molecules 2024, 29(7), 1538; https://doi.org/10.3390/molecules29071538 (registering DOI) - 29 Mar 2024
Abstract
Easy-to-handle N-hydroxyacridinecarbimidoyl chloride hydrochlorides were synthesized as convenient nitrile oxide precursors in the preparation of 3-(acridin-9/2-yl)isoxazole derivatives via 1,3-dipolar cycloaddition with terminal alkynes, 1,1-dichloroethene, and acrylonitrile. Azirines with an acridin-9/2-yl substituent attached directly or via the 1,2,3-triazole linker to the azirine C2 [...] Read more.
Easy-to-handle N-hydroxyacridinecarbimidoyl chloride hydrochlorides were synthesized as convenient nitrile oxide precursors in the preparation of 3-(acridin-9/2-yl)isoxazole derivatives via 1,3-dipolar cycloaddition with terminal alkynes, 1,1-dichloroethene, and acrylonitrile. Azirines with an acridin-9/2-yl substituent attached directly or via the 1,2,3-triazole linker to the azirine C2 were also synthesized. The three-membered rings of the acridine–azirine hybrids were found to be resistant to irradiation in the UV/visible boundary region, despite their long-wave absorption at 320–420 nm, indicating that the acridine moiety cannot be used as an antenna to transfer light energy to generate nitrile ylides from azirines for photoclick cycloaddition. The acridine–isoxazole hybrids linked at the C9–C3 or C2–C3 atoms under blue light irradiation underwent the addition of such hydrogen donor solvents, such as, toluene, o-xylene, mesitylene, 4-chlorotoluene, THF, 1,4-dioxane, or methyl tert-butyl ether (MTBE), to the acridine system to give the corresponding 9-substituted acridanes in good yields. The synthesized acridine–azirine, acridine–isoxazole, and acridane–isoxazole hybrids exhibited cytotoxicity toward both all tested cancer cell lines (HCT 116, MCF7, and A704) and normal cells (WI-26 VA4). Full article
(This article belongs to the Section Organic Chemistry)
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21 pages, 4732 KiB  
Article
Electrodeposition of Nanostructured Co–Cu Thin Alloy Films on to Steel Substrate from an Environmentally Friendly Novel Lactate Bath under Different Operating Conditions
by Raiedhah A. Alsaiari, Medhat M. Kamel and Mervate M. Mohamed
Coatings 2024, 14(4), 407; https://doi.org/10.3390/coatings14040407 (registering DOI) - 29 Mar 2024
Abstract
A new lactate bath was proposed to deposit Co–Cu thin alloy films in nanostructure form onto a steel cathode. The deposition bath contained CuSO4.5H2O, CoSO4.7H2O, CH3CHOHCOOH, and anhydrous Na2SO4 at [...] Read more.
A new lactate bath was proposed to deposit Co–Cu thin alloy films in nanostructure form onto a steel cathode. The deposition bath contained CuSO4.5H2O, CoSO4.7H2O, CH3CHOHCOOH, and anhydrous Na2SO4 at pH 10. The effects of [Co2+]/[Cu2+] molar ratios, lactate ion concentration, current density (CD), and bath temperature on cathodic polarization, cathodic current efficacy (CCE), composition, and structure of the Co–Cu alloys were investigated. The new bath had a high cathodic current efficiency of 85%, which increased with the applied CD. However, it decreased as the temperature increased. The produced coatings have an atomic percentage of Cu ranging from 19.8 to 99%. The deposition of the Co–Cu alloy belonged to regular codeposition. The Co content of the deposit increased with the amount of Co2+ ions in the bath, lactate concentration, and current density but decreased as the temperature increased. Cobalt hexagonal close-packed (HCP) and copper-rich, face-centered cubic (FCC) Co–Cu phases combine to form the polycrystalline structure of the electrodeposited Co–Cu alloy. The average crystallite size ranges between 46 and 89 nm. Energy dispersive X-ray (EDX) examination confirmed that the deposit contained Cu and Co metals. The throwing power and throwing index of the alkaline lactate bath were evaluated and found to be satisfactory. Full article
(This article belongs to the Special Issue Thin-Film Synthesis, Characterization and Properties)
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22 pages, 1477 KiB  
Review
The Role of NRF2 in Cerebrovascular Protection: Implications for Vascular Cognitive Impairment and Dementia (VCID)
by Yizhou Hu, Feng Zhang, Milos Ikonomovic and Tuo Yang
Int. J. Mol. Sci. 2024, 25(7), 3833; https://doi.org/10.3390/ijms25073833 (registering DOI) - 29 Mar 2024
Abstract
Vascular cognitive impairment and dementia (VCID) represents a broad spectrum of cognitive decline secondary to cerebral vascular aging and injury. It is the second most common type of dementia, and the prevalence continues to increase. Nuclear factor erythroid 2-related factor 2 (NRF2) is [...] Read more.
Vascular cognitive impairment and dementia (VCID) represents a broad spectrum of cognitive decline secondary to cerebral vascular aging and injury. It is the second most common type of dementia, and the prevalence continues to increase. Nuclear factor erythroid 2-related factor 2 (NRF2) is enriched in the cerebral vasculature and has diverse roles in metabolic balance, mitochondrial stabilization, redox balance, and anti-inflammation. In this review, we first briefly introduce cerebrovascular aging in VCID and the NRF2 pathway. We then extensively discuss the effects of NRF2 activation in cerebrovascular components such as endothelial cells, vascular smooth muscle cells, pericytes, and perivascular macrophages. Finally, we summarize the clinical potential of NRF2 activators in VCID. Full article
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17 pages, 12160 KiB  
Article
The Initiation Characteristics of Corrosion Fatigue Crack in 18Ni (250) Steel
by Hongzhang Pan, Yongmei Zhu and Mingjiang Fang
J. Mar. Sci. Eng. 2024, 12(4), 580; https://doi.org/10.3390/jmse12040580 (registering DOI) - 29 Mar 2024
Abstract
Maraging steel is the material of deep sea pressure equipment. The characteristics of corrosion fatigue crack initiation in 18Ni (250) were investigated by performing a tensile fatigue test under different loading conditions. The mechanism of corrosion fatigue crack initiation was analyzed considering the [...] Read more.
Maraging steel is the material of deep sea pressure equipment. The characteristics of corrosion fatigue crack initiation in 18Ni (250) were investigated by performing a tensile fatigue test under different loading conditions. The mechanism of corrosion fatigue crack initiation was analyzed considering the influence of welding. The results showed that the crack initiation life decreases with increasing load and increases with the stress ratio. In a corrosive seawater environment, crack initiation is affected by both mechanical damage and electrochemical corrosion. The proportion of the crack initiation life of the total sample life is approximately 71.45–99.55%, where the larger this proportion is, the smaller the fatigue zone is. Crack initiation and microcrack propagation in maraging steel correspond to the microfracture mechanism of dimple fractures. The microfracture mechanism is strongly affected by the presence of a weld but weakly affected by the weld position. The results of this study provide a theoretical basis for predicting the corrosion fatigue life of deep-sea submersible pressure hulls. Full article
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25 pages, 10664 KiB  
Article
Coaxial 3D Bioprinting Process Research and Performance Tests on Vascular Scaffolds
by Jiarun Sun, Youping Gong, Manli Xu, Huipeng Chen, Huifeng Shao and Rougang Zhou
Micromachines 2024, 15(4), 463; https://doi.org/10.3390/mi15040463 (registering DOI) - 29 Mar 2024
Abstract
Three-dimensionally printed vascularized tissue, which is suitable for treating human cardiovascular diseases, should possess excellent biocompatibility, mechanical performance, and the structure of complex vascular networks. In this paper, we propose a method for fabricating vascularized tissue based on coaxial 3D bioprinting technology combined [...] Read more.
Three-dimensionally printed vascularized tissue, which is suitable for treating human cardiovascular diseases, should possess excellent biocompatibility, mechanical performance, and the structure of complex vascular networks. In this paper, we propose a method for fabricating vascularized tissue based on coaxial 3D bioprinting technology combined with the mold method. Sodium alginate (SA) solution was chosen as the bioink material, while the cross-linking agent was a calcium chloride (CaCl2) solution. To obtain the optimal parameters for the fabrication of vascular scaffolds, we first formulated theoretical models of a coaxial jet and a vascular network. Subsequently, we conducted a simulation analysis to obtain preliminary process parameters. Based on the aforementioned research, experiments of vascular scaffold fabrication based on the coaxial jet model and experiments of vascular network fabrication were carried out. Finally, we optimized various parameters, such as the flow rate of internal and external solutions, bioink concentration, and cross-linking agent concentration. The performance tests showed that the fabricated vascular scaffolds had levels of satisfactory degradability, water absorption, and mechanical properties that meet the requirements for practical applications. Cellular experiments with stained samples demonstrated satisfactory proliferation of human umbilical vein endothelial cells (HUVECs) within the vascular scaffold over a seven-day period, observed under a fluorescent inverted microscope. The cells showed good biocompatibility with the vascular scaffold. The above results indicate that the fabricated vascular structure initially meet the requirements of vascular scaffolds. Full article
(This article belongs to the Special Issue Microfluidics and 3D Printing for Biomedical Applications)
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15 pages, 4451 KiB  
Article
Understanding Antidiabetic Potential of Oligosaccharides from Red Alga Dulse Devaleraea inkyuleei Xylan by Investigating α-Amylase and α-Glucosidase Inhibition
by Martin Alain Mune Mune, Tadashi Hatanaka, Hideki Kishimura and Yuya Kumagai
Molecules 2024, 29(7), 1536; https://doi.org/10.3390/molecules29071536 (registering DOI) - 29 Mar 2024
Abstract
In this study, the α-glucosidase (maltase-glucoamylase: MGAM) and α-amylase inhibitory properties elicited by xylooligosaccharides (XOSs) prepared from dulse xylan were analysed as a potential mechanism to control postprandial hyperglycaemia for type-2 diabetes prevention and treatment. Xylan was purified from red alga dulse powder [...] Read more.
In this study, the α-glucosidase (maltase-glucoamylase: MGAM) and α-amylase inhibitory properties elicited by xylooligosaccharides (XOSs) prepared from dulse xylan were analysed as a potential mechanism to control postprandial hyperglycaemia for type-2 diabetes prevention and treatment. Xylan was purified from red alga dulse powder and used for enzymatic hydrolysis using Sucrase X to produce XOSs. Fractionation of XOSs produced xylobiose (X2), β-(1→3)-xylosyl xylobiose (DX3), xylotriose (X3), β-(1→3)-xylosyl-xylotriose (DX4), and a dulse XOS mixture with n ≥ 4 xylose units (DXM). The different fractions exhibited moderate MGAM (IC50 = 11.41–23.44 mg/mL) and α-amylase (IC50 = 18.07–53.04 mg/mL) inhibitory activity, which was lower than that of acarbose. Kinetics studies revealed that XOSs bound to the active site of carbohydrate digestive enzymes, limiting access to the substrate by competitive inhibition. A molecular docking analysis of XOSs with MGAM and α-amylase clearly showed moderate strength of interactions, both hydrogen bonds and non-bonded contacts, at the active site of the enzymes. Overall, XOSs from dulse could prevent postprandial hyperglycaemia as functional food by a usual and continuous consumption. Full article
(This article belongs to the Special Issue Marine Bioactives for Human Health)
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17 pages, 326 KiB  
Article
Exploring the Underlying Barriers for the Successful Transition for Women from Higher Education to Employment in Egypt: A Focus Group Study
by Muhammad Qasim Rana, Shadia Fahim, Mohammed Saad, Angela Lee, Olugbenga Timo Oladinrin and Lekan Damilola Ojo
Soc. Sci. 2024, 13(4), 195; https://doi.org/10.3390/socsci13040195 (registering DOI) - 29 Mar 2024
Abstract
Education is the foundation of culture and the engine of economies; it is an essential part of life. However, it remains inaccessible or unavailable in some parts of developing nations. Moreover, such barriers for girls and women can extend beyond education and into [...] Read more.
Education is the foundation of culture and the engine of economies; it is an essential part of life. However, it remains inaccessible or unavailable in some parts of developing nations. Moreover, such barriers for girls and women can extend beyond education and into the workplace, and this is a bone of contention based on erroneous beliefs and other factors. Barriers for girls’ and women’s education are debatable in the literature; however, there is a sparsity of literature that focuses on the bridge to the workplace. Therefore, through a focus group study, this study explores the barriers that prohibit the transition for women from higher education to employment in Egypt. Based on qualitative data from focus group participants, the barriers to girls’ and women’s education are related to cultural, economic, family, and structural–educational barriers. In addition, stereotypical thinking and discrimination are factors hindering girls and women from ‘decent’ employment in Egypt. Based on this study’s results, some practical recommendations were elicited, which centre around awareness enhancement, formulation of laws and policies, and development of employability skills and entrepreneurship skills. The managerial and societal implications of this study are illustrated. It is anticipated that the results of this study will serve to create an inherent need to undertake a larger survey to investigate the barriers from a wider number of respondents. Full article
(This article belongs to the Section Work, Employment and the Labor Market)
10 pages, 1359 KiB  
Article
Association between Preoperative C-Reactive Protein-to-Albumin Ratio and Mortality after Plastic and Reconstructive Surgery
by Ah Ran Oh, Ha Min Sung, Jungchan Park, Gayoung Jin, So Myung Kong, Minsu Jung and Sangmin Maria Lee
J. Clin. Med. 2024, 13(7), 1998; https://doi.org/10.3390/jcm13071998 (registering DOI) - 29 Mar 2024
Abstract
Background: Prognostic markers have not been extensively studied in plastic and reconstructive surgery. Objective: We aimed to evaluate the prognostic value of preoperative C-reactive protein (CRP)-to-albumin ratio (CAR) in plastic and reconstructive surgery and to compare it with the neutrophil-to-lymphocyte ratio (NLR), [...] Read more.
Background: Prognostic markers have not been extensively studied in plastic and reconstructive surgery. Objective: We aimed to evaluate the prognostic value of preoperative C-reactive protein (CRP)-to-albumin ratio (CAR) in plastic and reconstructive surgery and to compare it with the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and modified Glasgow prognostic score (mGPS). Methods: From January 2011 to July 2019, we identified 2519 consecutive adult patients who were undergoing plastic and reconstructive surgery with available preoperative CRP and albumin levels. The receiver operating characteristic (ROC) curve was generated to evaluate predictability and estimate the threshold. The patients were divided according to this threshold, and the risk was compared. The primary outcome was one-year mortality, and the overall mortality was also analyzed. Results: The one-year mortality was 4.9%. The CAR showed an area under the ROC curve of 0.803, which was higher than those of NLR, PLR, and mGPS. According to the estimated threshold of 1.05, the patients were divided into two groups; 1585 (62.9%) were placed in the low group, and 934 (37.1%) were placed in the high group. After inverse probability weighting, the mortality rate during the first year after plastic and reconstructive surgery was significantly increased in the high group (1.3% vs. 10.9%; hazard ratio, 2.88; 95% confidence interval, 2.17–3.83; p < 0.001). Conclusions: In this study, high CAR was significantly associated with one-year mortality of patients after plastic and reconstructive surgery. Further studies are needed on prognostic markers in plastic and reconstructive surgery. Full article
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9 pages, 366 KiB  
Article
Speech Audiometry: The Development of Lithuanian Bisyllabic Phonemically Balanced Word Lists for Evaluation of Speech Recognition
by Vija Vainutien?, Justinas Iva?ka, Vytautas Kardelis, Tatjana Iva?kien? and Eugenijus Lesinskas
Appl. Sci. 2024, 14(7), 2897; https://doi.org/10.3390/app14072897 (registering DOI) - 29 Mar 2024
Abstract
Background and Objectives: Speech audiometry employs standardized materials, typically in the language spoken by the target population. Language-specific nuances, including phonological features, influence speech perception and recognition. The material of speech audiometry tests for the assessment of word recognition comprises lists of words [...] Read more.
Background and Objectives: Speech audiometry employs standardized materials, typically in the language spoken by the target population. Language-specific nuances, including phonological features, influence speech perception and recognition. The material of speech audiometry tests for the assessment of word recognition comprises lists of words that are phonemically or phonetically balanced. As auditory perception is influenced by a variety of linguistic features, it is necessary to develop test materials for the listener’s mother tongue. The objective of our study was to compose and evaluate new lists of Lithuanian words to assess speech recognition abilities. Materials and Methods: The main criteria for composing new lists of Lithuanian words included the syllable structure and frequency, the correlation between consonant and vowel phonemes, the frequency of specific vowel and consonant phonemes, word familiarity and rate. The words for the new lists were chosen from the Frequency Dictionary of Written Lithuanian according to the above criteria. Word recognition was assessed at different levels of presentations. The word list data were analyzed using a linear mixed-effect model for repeated measures. Results: Two hundred bisyllabic words were selected and organized into four lists. The results showed no statistically significant difference between the four sets of words. The interaction of the word list and presentation level was not statistically significant. Conclusions: Monaural performance functions indicated good inter-list reliability with no significant differences between the word recognition scores on the different bisyllabic word lists at each of the tested intensities. The word lists developed are equivalent, reliable and can be valuable for assessing speech recognition in a variety of conditions, including diagnosis, hearing rehabilitation and research. Full article
(This article belongs to the Special Issue Audio, Speech and Language Processing)
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19 pages, 2303 KiB  
Review
Exploring Factors Shaping Farmer Behavior in Wastewater Utilization for Agricultural Practices: A Rapid Review
by Laura Mirra, Simone Russo and Massimiliano Borrello
Sustainability 2024, 16(7), 2870; https://doi.org/10.3390/su16072870 (registering DOI) - 29 Mar 2024
Abstract
In recent years, circular economy strategies have gained attention in agriculture, particularly regarding the utilization of wastewater as an alternative water source. This study employs a rapid review methodology to examine farmers’ attitudes toward wastewater use in agriculture. By analyzing studies in literature [...] Read more.
In recent years, circular economy strategies have gained attention in agriculture, particularly regarding the utilization of wastewater as an alternative water source. This study employs a rapid review methodology to examine farmers’ attitudes toward wastewater use in agriculture. By analyzing studies in literature published from 2000 to 2023, this review identifies the key factors influencing farmers’ adoption of wastewater irrigation. These findings are valuable for policymakers seeking to develop targeted policies that support and encourage the adoption of wastewater irrigation, thereby contributing to sustainable water resource management. Full article
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13 pages, 584 KiB  
Article
Thermochemical Pretreatment for Improving the Psychrophilic Anaerobic Digestion of Coffee Husks
by Tzyy Shyuan Yang, Carla Flores-Rodriguez, Lorena Torres-Albarracin and Ariovaldo José da Silva
Methane 2024, 3(2), 214-226; https://doi.org/10.3390/methane3020013 (registering DOI) - 29 Mar 2024
Abstract
Psychrophilic anaerobic digestion emerges as an appealing integrated solution for the management of agricultural waste, particularly for farmers in regions where the average temperature does not exceed 26 °C, as seen in coffee cultivation. Therefore, this study seeks to assess the biomethane potential [...] Read more.
Psychrophilic anaerobic digestion emerges as an appealing integrated solution for the management of agricultural waste, particularly for farmers in regions where the average temperature does not exceed 26 °C, as seen in coffee cultivation. Therefore, this study seeks to assess the biomethane potential of thermochemical-treated coffee husk through psychrophilic anaerobic digestion (C3-20 °C-w/pretreatment). To examine its viability, outcomes were compared with reactors operating at both mesophilic (C1-35 °C) and psychrophilic (C2-20 °C) conditions, albeit without the use of pretreated coffee husk. The C3-20 °C-w/pretreatment test demonstrated a 36.89% increase (150.47 NmL CH4/g VS; 161.04 NmL CH4/g COD), while the C1-35 °C test exhibited a 24.03% increase (124.99 NmL CH4/g VS; 133.77 NmL CH4/g COD), both in comparison to the C2-20 °C test (94.96 NmL CH4/g VS; 101.63 NmL CH4/g COD). Notably, the C3-20 °C-w/pretreatment trial yielded superior outcomes, accompanied by an associated energy output of 3199.25 GWh/year, sufficient to meet the annual energy demands of 494 residences. This marks an increase of 83 and 182 million residences compared to the mesophilic and psychrophilic AD of CH without pretreatment, respectively. Full article
(This article belongs to the Special Issue Anaerobic Digestion Process: Converting Waste to Energy)
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19 pages, 3351 KiB  
Article
Fourier Transform Infrared Spectroscopy Tracking of Fermentation of Oat and Pea Bases for Yoghurt-Type Products
by Olivia Greulich, Lene Duedahl-Olesen, Mette Skau Mikkelsen, J?rn Smedsgaard and Claus Heiner Bang-Berthelsen
Fermentation 2024, 10(4), 189; https://doi.org/10.3390/fermentation10040189 (registering DOI) - 29 Mar 2024
Abstract
The fermentation process of plant-based yoghurt (PBY)-like products must be followed for consistency by monitoring, e.g., the pH, temperature, and lactic acid concentration. Spectroscopy provides an efficient multivariate in situ quality monitoring method for tracking the process. Therefore, quality monitoring methods for pea- [...] Read more.
The fermentation process of plant-based yoghurt (PBY)-like products must be followed for consistency by monitoring, e.g., the pH, temperature, and lactic acid concentration. Spectroscopy provides an efficient multivariate in situ quality monitoring method for tracking the process. Therefore, quality monitoring methods for pea- and oat-based yoghurt-like products using Fourier transform infrared (FT-IR) spectroscopy and high-performance liquid chromatography (HPLC) were developed and modeled. Plant-based yoghurt (PBY) was formulated by fermenting pea and oat plant drinks with a commercial starter culture based on Lactobacillus and Streptococcus strains. The main variance during fermentation was explained by spectral carbohydrate and protein bands with a notable shift in protein band peaks for the amide II band at 1548 cm−1 to 1576 cm−1. In addition to the identification of changed spectral bands during fermentation, FT-IR efficiently tracked the variation in oat and pea fermentation using pH as the main indicator. Prediction models with an R2 for the predicted value of pH as a fermentation indicator (R2 = 0.941) with a corresponding root-mean-squared error of prediction (RMSEP) of 0.247 was obtained when compared to the traditional pH method. Full article
(This article belongs to the Special Issue Application of Lactobacillus in Fermented Food and Beverages)
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17 pages, 1129 KiB  
Article
Effect of Intermittent Low-Pressure Radiofrequency Helium Cold Plasma Treatments on Rice Gelatinization, Fatty Acid, and Hygroscopicity
by Ziyi Cao, Xingjun Li, Hongdong Song, Yu Jie and Chang Liu
Foods 2024, 13(7), 1056; https://doi.org/10.3390/foods13071056 (registering DOI) - 29 Mar 2024
Abstract
To establish the safe and reproducible effects of cold plasma (CP) technology on food products, this study evaluated the gelatinization parameters, fatty acid profile, and hygroscopic properties of rice grains repeatedly treated with low-pressure radiofrequency (RF) helium CP (13.56 MHz, 140 Pa, 120 [...] Read more.
To establish the safe and reproducible effects of cold plasma (CP) technology on food products, this study evaluated the gelatinization parameters, fatty acid profile, and hygroscopic properties of rice grains repeatedly treated with low-pressure radiofrequency (RF) helium CP (13.56 MHz, 140 Pa, 120 W-20s, 0–4 times, and 300 g sample). Compared with the untreated (zero times) sample, with an increase in CP treatment times from one to four on rice, the water contact angle and cooking time decreased, while the water absorption rate and freshness index increased, and the pH value remained unchanged. CP repeating treatments essentially had no effect on the gelatinization enthalpy, but significantly increased the peak temperature of gelatinization. From the pasting profile of rice that has been repeatedly CP treated, the peak, breakdown, and setback viscosities in flour paste decreased. CP repeating treatments on rice did not change the short-range molecular order of starch. Compared with the untreated sample, the first helium CP treatment maintained the content of C18:1n9c, C18:2n6c, and C18:3n3, but the second to fourth CP treatment significantly decreased contents of these fatty acids (FAs) as the C18:0 content increased. The first three CP treatments can increase the water and sucrose solvent retention capacity in rice flours. CP repeatedly treated rice first exhibits the similar monolayer water content and solid surface area of water sorption. Principal component analysis shows that contact angle, pasting parameters, and fatty acid profile in milled rice are quite sensitive to CP treatment. Results support that the effect of low-pressure RF 120W helium CP treatment 20 s on rice grains is perdurable, and the improvement of CP intermittent treatments on rice cooking and pasting properties is an added benefit, and the hygroscopic properties of rice was kept. Full article
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13 pages, 3332 KiB  
Article
Procymidone Application Contributes to Multidrug Resistance of Botrytis cinerea
by Zhaochen Wu, Chuxian Yu, Qiuyan Bi, Junting Zhang, Jianjun Hao, Pengfei Liu and Xili Liu
J. Fungi 2024, 10(4), 261; https://doi.org/10.3390/jof10040261 (registering DOI) - 29 Mar 2024
Abstract
The necrotrophic pathogen Botrytis cinerea infects a broad range of plant hosts and causes substantial economic losses to many crops. Although resistance to procymidone has been observed in the field, it remains uncertain why procymidone is usually involved in multidrug resistance (MDR) together [...] Read more.
The necrotrophic pathogen Botrytis cinerea infects a broad range of plant hosts and causes substantial economic losses to many crops. Although resistance to procymidone has been observed in the field, it remains uncertain why procymidone is usually involved in multidrug resistance (MDR) together with other fungicides. Nine mutants derived from the B. cinerea strain B05.10 through procymidone domestication exhibited high resistance factors (RFs) against both procymidone and fludioxonil. However, the fitness of the mutants was reduced compared to their parental strain, showing non-sporulation and moderate virulence. Furthermore, the RFs of these mutants to other fungicides, such as azoxystrobin, fluazinam, difenoconazole, and pyrimethanil, ranged from 10 to 151, indicating the occurrence of MDR. Transcriptive expression analysis using the quantitative polymerase chain reaction (qPCR) revealed that the mutants overexpressed ABC transporter genes, ranging from 2 to 93.7-fold. These mutants carried single-point mutations W647X, R96X, and Q751X within BcBos1 by DNA sequencing. These alterations in BcBos1 conferred resistance to procymidone and other fungicides in the mutants. Molecular docking analysis suggested distinct interactions between procymidone and Bos1 in the B. cinerea standard strain B05.10 or the resistant mutants, suggesting a higher affinity of the former towards binding with the fungicide. This study provides a comprehensive understanding of the biological characteristics of the resistant mutants and conducts an initial investigation into its fungicide resistance traits, providing a reference for understanding the causes of multidrug resistance of B. cinerea in the field. Full article
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14 pages, 2604 KiB  
Article
Effect of Plasma Treatment on Bamboo Fiber-Reinforced Epoxy Composites
by Pornchai Rachtanapun, Choncharoen Sawangrat, Thidarat Kanthiya, Parichat Thipchai, Kannikar Kaewapai, Jonghwan Suhr, Patnarin Worajittiphon, Nuttapol Tanadchangsaeng, Pitiwat Wattanachai and Kittisak Jantanasakulwong
Polymers 2024, 16(7), 938; https://doi.org/10.3390/polym16070938 (registering DOI) - 29 Mar 2024
Abstract
Bamboo cellulose fiber (BF)-reinforced epoxy (EP) composites were fabricated with BF subjected to plasma treatment using argon (Ar), oxygen (O2), and nitrogen (N2) gases. Optimal mechanical properties of the EP/BF composites were achieved with BFs subjected to 30 min [...] Read more.
Bamboo cellulose fiber (BF)-reinforced epoxy (EP) composites were fabricated with BF subjected to plasma treatment using argon (Ar), oxygen (O2), and nitrogen (N2) gases. Optimal mechanical properties of the EP/BF composites were achieved with BFs subjected to 30 min of plasma treatment using Ar. This is because Ar gas improved the plasma electron density, surface polarity, and BF roughness. Flexural strength and flexural modulus increased with O2 plasma treatment. Scanning electron microscopy images showed that the etching of the fiber surface with Ar gas improved interfacial adhesion. The water contact angle and surface tension of the EP/BF composite improved after 10 min of Ar treatment, owing to the compatibility between the BFs and the EP matrix. The Fourier transform infrared spectroscopy results confirmed a reduction in lignin after treatment and the formation of new peaks at 1736 cm−1, which indicated a reaction between epoxy groups of the EP and carbon in the BF backbone. This reaction improved the compatibility, mechanical properties, and water resistance of the composites. Full article
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21 pages, 3280 KiB  
Article
Rare-Earth Element Phase Associations in Four West Virginia Coal Samples
by Rachel Yesenchak, Shikha Sharma, Christina Lopano and Scott Montross
Minerals 2024, 14(4), 362; https://doi.org/10.3390/min14040362 (registering DOI) - 29 Mar 2024
Abstract
Rare-earth elements are critical components of technologies used in renewable energy, communication, transportation, and national defense. Securing supply chains by developing domestic rare-earth resources, including coal and coal byproducts, has become a national priority. With some of the largest coal reserves in the [...] Read more.
Rare-earth elements are critical components of technologies used in renewable energy, communication, transportation, and national defense. Securing supply chains by developing domestic rare-earth resources, including coal and coal byproducts, has become a national priority. With some of the largest coal reserves in the country, states within the Appalachian Basin can play a key role in supplying these elements. Understanding rare-earth element phase associations and the processes that lead to enrichment in these coals will inform resource prospecting and recovery techniques. This study used sequential leaching in addition to scanning electron microscopy and energy-dispersive X-ray spectroscopy to identify rare-earth element modes of occurrence in WV coals. The results indicate that heavier elements have a stronger association with organic matter and that phosphate minerals are primary sources of both heavy and light rare-earth elements. However, these phases are shielded by a resistant aluminosilicate matrix that can impede the recovery of rare-earth elements using traditional methods. Full article
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17 pages, 17783 KiB  
Article
Numerical Simulation of Flow Characteristics for Supercritical CO2-Sprayed Polyurethane Resin
by Chichao Li, Chengrui Zhang, Minghua Xiang, Qing Chen, Zhenyang Luo and Yanlong Luo
Polymers 2024, 16(7), 940; https://doi.org/10.3390/polym16070940 (registering DOI) - 29 Mar 2024
Abstract
Conventional paint spraying processes often use small molecule organic solvents and emit a large amount of volatile organic compounds (VOCs) that are highly toxic, flammable, and explosive. Alternatively, the spraying technology using supercritical CO2 (scCO2) as a solvent has attracted [...] Read more.
Conventional paint spraying processes often use small molecule organic solvents and emit a large amount of volatile organic compounds (VOCs) that are highly toxic, flammable, and explosive. Alternatively, the spraying technology using supercritical CO2 (scCO2) as a solvent has attracted attention because of its ability to reduce VOC emissions, but the flow characteristics of coatings have not been thoroughly studied. Therefore, we numerically simulate the spraying process based on the actual process of scCO2 spraying polyurethane coatings by computational fluid dynamics (CFD). The effects of inlet pressure and volume fraction of scCO2 on the fluid motion parameters inside the nozzle as well as the atomization effect of droplets outside the nozzle are investigated. The simulated results show that a fluid with a large volume fraction of scCO2 will obtain a smaller density, resulting in a larger velocity and a larger distance for the spray to effectively spray. Higher coating content and bigger inlet pressures will result in higher discrete phase model (DPM) concentrations, and thus a bigger inlet pressure should be used to make the droplets more uniform across the 30° spray range. This study can provide theoretical guidance for the process of scCO2-sprayed polyurethane resin. Full article
(This article belongs to the Special Issue Preparation and Application of Rubber Composites)
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22 pages, 1204 KiB  
Review
Gluten-Free Diet and Other Celiac Disease Therapies: Current Understanding and Emerging Strategies
by Anna Maria Mazzola, Irene Zammarchi, Maria Chiara Valerii, Enzo Spisni, Ilaria Maria Saracino, Francesco Lanzarotto and Chiara Ricci
Nutrients 2024, 16(7), 1006; https://doi.org/10.3390/nu16071006 (registering DOI) - 29 Mar 2024
Abstract
A lifelong gluten-free diet (GFD) is the only treatment for celiac disease and other gluten-related disorders. Nevertheless, strict adherence to the GFD is often challenging due to concerns about social isolation, risk of gluten contaminations, high cost, poor quality and the taste of [...] Read more.
A lifelong gluten-free diet (GFD) is the only treatment for celiac disease and other gluten-related disorders. Nevertheless, strict adherence to the GFD is often challenging due to concerns about social isolation, risk of gluten contaminations, high cost, poor quality and the taste of gluten-free products. Moreover, although the GFD is effective in achieving mucosal healing, it may lead to dietary imbalances due to nutrient deficiencies over a long period of time. To overcome these issues, several gluten-free wheat flours have been developed to create products that closely resemble their gluten-containing counterparts. Furthermore, given the critical importance of adhering to the GFD, it becomes essential to promote adherence and monitor possible voluntary or involuntary transgressions. Various methods, including clinical assessment, questionnaires, serology for celiac disease, duodenal biopsies and the detection of Gluten Immunogenic Peptides (GIPs) are employed for this purpose, but none are considered entirely satisfactory. Since adherence to the GFD poses challenges, alternative therapies should be implemented in the coming years to improve treatment efficacy and the quality of life of patients with celiac disease. The aim of this narrative review is to explore current knowledge of the GFD and investigate its future perspectives, focusing on technology advancements, follow-up strategies and insights into a rapidly changing future. Full article
(This article belongs to the Special Issue Food Intolerance and Food Allergy: Novel Aspects in a Changing World)
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19 pages, 8492 KiB  
Article
Spike Device with Worm Gear Unit for Driving Wheels to Improve the Traction Performance of Compact Tractors on Grass Plots
by Rudolf Abrahám, Radoslav Majdan, Katarína Kollárová, Zdenko Tká?, Eva Matejková, Soňa Masarovi?ová and Róbert Drli?ka
Agriculture 2024, 14(4), 545; https://doi.org/10.3390/agriculture14040545 (registering DOI) - 29 Mar 2024
Abstract
In general, energy loss reduction via the interaction of tires with the ground improves tractor traction performance when a drawbar pull is generated. This paper is examines the driving wheels with steel spikes for a tractor equipped with modern radial tires. An improved [...] Read more.
In general, energy loss reduction via the interaction of tires with the ground improves tractor traction performance when a drawbar pull is generated. This paper is examines the driving wheels with steel spikes for a tractor equipped with modern radial tires. An improved design of the spike device that allows for the change between an active and inactive position of the spikes is presented. The traction performance of a compact articulated tractor with the spike device was tested on a grass plot with two soil moisture contents (SMC). The highest difference in the drawbar pull in the range from 14.2% to 40.5% and from 17.1% to 36.8% was reached by the spikes in the active position in comparison with the tires without spikes, which were at the slip range from 45% to 5% in the case of the low SMC when the test tractor was in the 3rd and 1st gear. The motion resistance difference between the spikes in the active position and the tires without spikes was 11.8% and 2.5% at the low and medium SMC, respectively. At the low and medium SMC, the highest tractive efficiency of 0.765 (0.721) and 0.757 (0.731) was reached by the spikes in the active position when the test tractor was in the 1st (3rd) gear in comparison with 0.736 (0.7) and 0.723 (0.708) in the case of the tires without spikes. The results indicated that the spike device allowed for the improvement of tractor tractive performance. Full article
(This article belongs to the Section Agricultural Technology)
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